What are biofilms? Biofilms are protective communities where various forms of the Lyme bacteria can hide from prescriptive antibiotics, herbal antimicrobials, and the immune system. In chronic Lyme and associated diseases they can cause treatment resistance and relapse once antibiotics or herbal antimicrobials are stopped. In biofilms bacteria produce and cover themselves in a layer of slime composed of mucopolysaccharides.
To add structure, the bacteria recruit a protein found in blood called fibrinogen which they then convert to the protein fibrin. Because the fibrin gives structure, the bacteria in biofilms can rid themselves of their outer protein coverings making it harder for the immune system to react against them. In addition the slime layer covers the germs so the immune system cannot see them and antibiotics or antimicrobial supplements cannot reach the germs. Within the biofilms the germs establish highly organized structures and functions where they communicate using various chemical messengers, excrete waste through channels and perform other complex activities to promote the longevity of the community.
Eva Sapi PhD and her colleagues are performing groundbreaking Lyme Disease research. In the past 2 years she has published two articles based on petri dish experiments in her lab. The first published over a year ago shows that the herbs Banderol and Samento used together completely eliminate biofilm communities and eradicate nearly every germ living in them. Her more recent study of 5 different antibiotics shows that prescription tinidazole decreases the size of biofilm communities and eliminates the germs living in them by over 90 percent.
Biofilms require calcium, magnesium and contain other minerals and heavy metals. Most believe that treating biofilms in the last four months of treatment prevents relapse or anytime in treatment when resistance to antibiotics or herbal antimicrobials is blocking progress. When treating biofilms, sometimes die-off Herxheimer reactions can occur. In a die off reaction the immune system makes more inflammatory chemicals that can temporarily make the Lyme and associated diseases symptoms worse.