Naltrexone is an FDA-approved opiate antagonist that has traditionally been used to wean alcoholics and opioid dependent drug users off the substances, but, in a low dose (referred to as “low dose naltrexone” which is approx. 1/10 the dose used for drug/alcohol rehabilitation), can boost the immune system — helping those with HIV/AIDS, cancer, autoimmune diseases, and central nervous system disorders.
Low dose naltrexone blocks the opiate receptor for about four hours which causes a rebound effect resulting in a dramatic increase in endogenous opiate production.
“Certain medications will work against the naltrexone such as Hydrocodone, Oxycodone, Oxymorphone and other opiate/opioid narcotics. These medications should not be taken while on Naltrexone, as nausea, vomiting, cold sweats, chills, and sometimes numbness in the limbs may occur. Naltrexone may also interfere or counteract both low and high doses of over-the-counter NSAID medications.”
Amazingly, LDN can reduce inflammation and oxidative stress, modulate the immune system, and even inhibit cancer cell proliferation.
LDN is generally used in doses ranging from 3-4.5 mg daily, but many people start at 1.4 mg and work their way up. People with multiple sclerosis (MS) and muscle spasticity tend to do better on a 3 mg dose than the standard 4.5 mg dose recommended for neurodegenerative disorders.
What Conditions Does LDN Treat ?